Lupkynis protects kidneys in lupus nephritis for up to 3 years
网页2023年7月24日 · The therapy is an oral medication approved in US, UK, and EU. by Margarida Maia July 24, 2023. Lupkynis (voclosporin) continues to be safe and to protect kidney function when taken for up to three years by patients with lupus nephritis, a kidney complication of lupus. That’s according to the full results from AURORA 2 …
1st patient enrolled in global Phase 2 trial of daxdilimab for...
网页2023年5月18日 · Horizon Therapeutics, the therapy’s developer, anticipates about 210 patients, ages 18–80, will enroll in the global study (NCT05540665), expected to span more than two years.. Recruitment is ongoing at sites in the U.S., Argentina, Brazil, Israel, Malaysia, Poland, Serbia, Spain, Taiwan, and Thailand.
Lupkynis helps protect kidneys with lupus nephritis and high...
网页2023年6月12日 · Lupkynis is approved in the U.S., European Union, and the U.K. as an oral treatment for adults with active lupus nephritis when combined with background immunosuppressant therapy, including mycophenolate mofetil and corticosteroids. It works by blocking the activity of a protein called calcineurin — a mechanism thought to reduce inflammation and stabilize kidney cells.
Phase 3 trials of ianalumab for SLE, lupus nephritis now enrolling
网页2023年6月15日 · All three trials are being sponsored by Novartis, the company developing ianalumab. Lupus Therapeutics, the clinical research affiliate of the Lupus Research Alliance, recently announced that it will be teaming up with Novartis to help run these trials at sites in North America. “We believe this collaboration between Lupus Therapeutics and Novartis Pharmaceuticals will provide a significant ...
Lupkynis approved in Japan to treat lupus nephritis
网页6 天之前 · Lupkynis (voclosporin) is now approved in Japan to treat lupus nephritis, a complication of lupus marked by kidney damage and inflammation. The Japanese Ministry of Health, Labour, and Welfare approved the treatment’s use in combination with the immunosuppressant mycophenolate mofetil. Otsuka Pharmaceutical filed a new drug application with ...
Lupus overview - Lupus News Today
网页2023年2月9日 · Lupus is a chronic disorder wherein the immune system attacks the body’s own healthy tissue. Lupus can affect virtually every part of the body, including the skin, kidneys, joints, brain, heart, and lungs, resulting in a range of symptoms. Systemic lupus erythematosus (SLE) — often referred to simply as lupus — is the most common and ...
LRA awards scientists $600K for work into new treatments for lupus
网页by Mary Chapman March 14, 2024. The Lupus Research Alliance (LRA) has announced the latest recipients of its Lupus Mechanisms and Targets Award (LMTA), who will investigate molecular pathways or targets that could lead to new or better treatments for lupus. Each of the seven awarded scientists will receive up to $600,000 in funding over three ...
Long-term safety of Lupkynis for SLE confirmed in AURORA trial
网页2023年4月10日 · New top-line data show participants in the Lupkynis treatment arm of the now completed Phase 3 AURORA trial (NCT03021499) had similar kidney biopsy (histologic) findings as those in the active control arm receiving mycophenolate mofetil, an immunosuppressant sold under the brand name CellCept, and low-dose steroids alone.. These results contrast with the well-known kidney-related side effects ...
Lupuzor Shows Strong Safety Results as Lupus Treatment in Phase …
网页by Alice Melão September 29, 2017. New data from an ongoing Phase 3 clinical trial continues to demonstrate that ImmuPharma ‘s Lupuzor is safe for the treatment of systemic lupus erythematosus (SLE) patients. To date, all trial participants have reached the six-month stage, and one out of four have completed the full 12-month study.
Lupus Talk: When Everyone Thinks They Have a Cure
网页2017年12月14日 · When Everyone Thinks They Have a Cure. by Shanelle Gabriel December 14, 2017. It was my umpteenth time in the ER for complications with lupus. My nurse was from the Caribbean (like many in this hospital in Flatbush, Brooklyn, New York), and he had a thick Jamaican accent. He came in to do a vitals check and asked if I’m chronically sick.