TRPV1

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1.
Scientists have long known that the nervous system receptor known as TRPV1 can affect sensations of pain in the body.
科学家一直知道神经系统受体如已知的TRPV1能影响机体的疼痛感觉。
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2.
The team found that this compound activated TRPV1 channels - which alone triggered long-term depression in the brain tissue.
她的团队发现这个成分激活TRPV1通道，它可以独自激发脑组织的长时程抑郁。
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3.
Study on role of TRPV1 and its mechanisms will help us to understand pain physiology and to develop new analgesic drugs.
深入研究TRPV1的作用机制，有助于理解痛觉生理和开发新型镇痛药物。
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4.
Thus, TRPV1 is an excellent target for a rational pharmacological treatment of pain.
因此，TRPV1是一个很好的目标，合理的药物治疗的痛苦。
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5.
Pain relief occurs after what is thought to be a reduction in TRPV1-expressing nociceptive nerve endings.
疼痛缓解后发生了被认为是在TRPV1受体，表达痛觉神经末梢减少。
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6.
When scientists discovered that the VR1 receptor was a member of the larger family of TRP ion channels, the VR1 receptor was renamed TRPV1.
科学家们发现VR1受体是瞬时受体电位通道（TRPionchannels）家族的一员，于是VR1受体又被命名为TRPV1。
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7.
TRPV1 can detect noxious stimulus and convert it into action potentials traveling to the central and forming pain sensation.
TRPV1能够感受伤害性刺激，将之转化为动作电位，传至中枢形成痛觉。
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8.
Other drugs aimed at reducing pain and inflammation by blocking or activating TRPV1 receptors are in the research pipeline.
其他药物的目的在于通过阻断或激活TRPV1受体减少疼痛和炎症，这还在研究中。
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9.
Further, rimonabant entirely blocked long-term depression by blocking TRPV1 channels.
另外，利莫那班通过阻断TRPV1通道完全阻断长时程抑郁。
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10.
When TRPV1 is activated or sensitized by proton, bradykinin, or endovanilloids released during myocardial ischemia (MI), it leads to angina.
心肌缺血时释放的质子，缓激肽，或内源性香草酸均能激动或致敏TRPV1，导致心绞痛。
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