Read on for more details. Both histamine-2 receptor antagonists (H2 blockers) and proton pump inhibitors (PPIs) decrease ...

Abstract and Introduction Predicting and Establishing the Clinical Efficacy of a Histamine H Application ... mechanisms of action of H 1-receptor antagonists and to predict their clinical efficacy.

1942—Antergan becomes the first antihistamine tested in humans and goes on the market. 1972—James Black discovers the H2 receptor and characterizes its antagonist, burimamide. 1999 ...

Ten years later, the Swiss-Italian physiologist Daniel Bovet synthesized the first antagonists ... discovery of H1, the number of known histamine receptors kept multiplying. The H2 receptor ...

The acid-reducing drugs include proton pump inhibitors such as omeprazole and esomeprazole, histamine H2-receptor antagonists, or H2 blockers, such as cimetidine and famotidine, and antacid ...

Abstract and Introduction Predicting and Establishing the Clinical Efficacy of a Histamine H Application of the Model Paradigm Conclusions References In vitro findings may correlate with the ...