*仅供医学专业人士阅读参考众所周知，APOE4是散发阿尔茨海默病（AD）的最强风险基因。大约三年前，首都医科大学宣武医院团队的一项研究显示，亚裔携带APOE4的频率为9%[1]。受影响的人可真不少。去年年底，斯坦福大学团队的一项研究结果表明，APOE ...

当ApoE被传递到转移细胞时，它会中和脂质，当铁死亡开始时脂质会迅速“燃烧”并破坏细胞膜，ApoE会增加细胞的抗氧化能力。综合起来，这些ApoE作用保护黑色素瘤细胞免于溶解，从而降低了体内铁下垂的治疗效果。

A research team led by Prof. Patrizia Agostinis (VIB-KU Leuven) has found that melanoma cell populations protect themselves ...

Researchers from the team of Prof. Patrizia Agostinis (VIB-KU Leuven) have found that melanoma cell populations protect themselves from a form of cell death called ferroptosis by secreting the ...

Corder, E.H. et al. HIV-infected subjects with the E4 allele for APOE have excess dementia and peripheral neuropathy. Nature Med. 4, 1182–1184 (1998).

Revvity, Inc. RVTY announced the launch of the in-vitro diagnostic EURORealTime APOE assay in European countries that accept the CE mark on Oct. 2. The assay will likely enable accurate genotyping of ...

A recent study suggests that a drug approved for the treatment of seizures may also help treat Alzheimer's in people who do ...

However, genetic risk factors for the vastly more common late-onset cases were not uncovered until 1993, when researchers zeroed in on APOE , a gene encoding a protein crucial to transporting fats ...

Revvity, Inc. RVTY announced the launch of the in-vitro diagnostic EURORealTime APOE assay in European countries that accept the CE mark on Oct. 2. The assay will likely enable accurate genotyping ...

A drug that has been used for nearly a century to prevent and dissolve blood clots may also delay the onset of Alzheimer’s disease, according to a study in the October 8 Molecular Psychiatry. Heparin ...

Michael Belloy at Washington University in St. Louis noted that the findings could help distinguish between genes that directly affect pathology, and those that instead help maintain cognition in the ...

Revvity, Inc. (NYSE: RVTY), announced today the launch of the in-vitro diagnostic EURORealTimeTM APOE assay in European countries that accept the CE mark, which will enable accurate genotyping of the ...