[45] The TCAs are effective agents in depression ... best tolerated and most studied TCA in this patient group. [47] Electrocardiograms must be obtained prior to beginning TCA therapy in the ...

He also joined a support group for retired men run by his senior center, which he enjoyed a lot. Choosing an antidepressant for an older patient can be complex. They're often already on many ...

More information: Sujita W. Narayan et al, Efficacy and safety of antidepressants for pain in older adults: A systematic review and meta‐analysis, British Journal of Clinical Pharmacology (2024 ...

The study found that in the last 40 years there have been only 15 trials globally focusing on the benefit of antidepressants for pain in older people. This study fills a much-needed gap in ...