Summary. Doripenem, a member of the β-lactam class of antibiotics, is the newest addition to the carbapenems. It exhibits concentration-independent bactericidal activity against gram-positive ...

These pathogens have reached high rates of resistance to multiple drugs, including last-resort antibiotics called carbapenems. In Italy, a G7 member state, carbapenem-resistance rate was 29% in 2019.

The emergence of resistant to carbapenems Gram-negative bacteria (CR GNB) has severely challenged antimicrobial therapy. Many CR GNB isolates are only susceptible to polymyxins; however ...

baumannii infections are resistant to carbapenems, with up to 95% of strains resistant in some countries. BioVersys’s lead product, BV100 (rifabutin for infusion), is in clinical development for ...

New research has identified the genetic elements responsible for turning classical Klebsiella pneumoniae, which generally infects only sick and/or immunocompromised people in the health care setting, ...

A new report from the CDC published Thursday found antimicrobial-resistant bacterial infections are spreading in Ukraine amid ...

Drugs called carbapenems are used when an infection cannot be treated with anything else. The spread of resistant Klebsiella pneumoniae was "extremely concerning", researchers from the Sanger ...

They include penicillin and its derivatives, such as methicillin and amoxicillin, as well as other groups of antibiotics known as the cephalosporins, carbapenems, and monobactams. The beta-lactam ring ...

Phare Bio has been awarded $27 million in funding from the Advanced Research Projects Agency for Health (ARPA-H). The biotech ...

Full vaccination against COVID-19 protects recipients from serious cardiovascular disease linked to COVID-19, according to a ...

A high rate of resistance was seen among UTI causing E. choli and Klebsiella pneumoniae and Acinetobacter baumannii against ...

Among Gram-negative bacteria –some of the most resistant to antimicrobial drugs – resistance to carbapenems increased more than any other type of antibiotic, from 127,000 in 1990 to 216,000 in ...