Improvements in levodopa pharmacokinetics with the addition ... safety and tolerability of entacapone with the most common side effects being increased dyskinesias, diarrhea and urine discoloration.
These side effects include: COMT inhibitors are ... They are usually prescribed in combination with carbidopa and levodopa.
In the study, the increase in "on" time without dyskinesia at week 12 was 2.72 hours for ABBV-951 versus 0.97 hours for oral levodopa/carbidopa, with decreases in "off" time of 2.75 hours and 0.96 ...
In patients with motor fluctuations, Stalevo provides the benefits seen by adding entacapone to levodopa/carbidopa ... familiarity with Stalevo and its side effects, most of which can be minimized ...