The good news: Most of the tested chemicals’ individual cytotoxicity and neurotoxicity levels were relatively low. The bad ...

Rat LD50 values were taken from the Registry of Toxic Effects of Chemical Substances (RTECS) database [55] and cytotoxicity values were taken from the public National Cancer Institute (NCI ...

综上所述，香菇多糖在体外和体内均表现出对Aβ和α-syn纤维聚集的抑制作用，并能够显著缓解其引起的神经毒性和行为缺陷。这些结果表明，香菇多糖可能作为一种潜在的治疗药物用于AD和PD的防治，这一研究为天然多糖类物质在神经退行性疾病中的应用提供了新的思路 ...

For the cytotoxicity model, which was constructed using a large number of records, multitask learning did not affect precision but did reduce computation time. The models developed here were used ...

Antibodies show promise as candidates for therapeutics as well as tools for advancing mechanistic studies of the HER family receptors.

The good news: Most of the tested chemicals' individual cytotoxicity and neurotoxicity levels were relatively low. The bad news: the chemicals acted together to make the entire mixture toxic.

SFA Therapeutics, Inc., a clinical-stage biopharmaceutical company developing oral small-molecule biosynthetic compounds for ...

Researchers hope to plan clinical trials of 5-fluorouracil with drugs that would enhance its RNA-damaging effects and kill ...

MacroGenics, Inc. (NASDAQ: MGNX), a biopharmaceutical company focused on discovering, developing, manufacturing and ...