Sera with positive GADA by radioassay from 14 subjects (7 ECL-GADA positive and 7 ECL-GADA negative) were incubated with different concentrations of unlabeled GAD65 protein and analyzed with ...

Researchers suspect the immune system's reaction is to a surplus of unique antibodies in the blood called anti-GAD65 antibodies. These antibodies, found in excess in most people with SPS, block the ...

Antibody profiling tools enhance immunology research, offering insights into humoral responses and vaccine efficacy through ...

In patients tested after 2019, antibodies against GAD65, Zinc4 and Tr were also included in the panel). Prior to 2019 GAD65 testing was done separately. In the patients with positive GAD65 antibodies, ...

Antigen-specific, vaccine-based approaches using β-cell-specific autoantigens to induce immune tolerance are under development and include glutamate decarboxylase 65 kDa isoform (GAD65 ...

Nature Neuroscience, 21(1): 29-32 Kosse C, Schöne C, Bracey E, Burdakov D (2017) Orexin-driven GAD65 network of the lateral hypothalamus sets physical activity in mice. Proceedings of the National ...

GAD65, IA-2, and/or ZnT8 longitudinally followed for 12 ± 3.7 years; and 181 age-matched, healthy, antibody-negative children. The ECL-GADA assay had a sensitivity similar to that of the standard ...