Proteins control most of the body's functions, and their malfunction can have severe consequences, such as neurodegenerative ...

Proteins control most of the body's functions, and their malfunction can have severe consequences, such as neurodegenerative diseases or cancer. Therefore, cells have mechanisms in place to control ...

GlobalData’s report assesses the drugs in the Heat Shock Protein 70 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline.

This useful study by Gao et al identifies Hspa2 as a heterogeneous transcript in the early embryo and proposes a plausible mechanism showing interactions with Carm1. The authors propose that ...

2024年9月26日，中国医学科学院、北京协和医学院詹启敏院士团队在期刊《Signal Transduction and Targeted Therapy》上发表了题为“GRP75 triggers white adipose tissue ...

How does a spider recycle its silk? To meet the high metabolic demands of daily silk production, at least some spiders have developed a way to reuse their silk. Certain orb web-weaving spiders recycle ...

通过多年的实践探索和思想凝练，我带领团队构建了系统的中药靶点发现技术方法群，阐明了多种传统中药活性成分的直接作用靶点，为诠释中药传统功效提供了现代科学证据，也为重大疾病治疗贡献了具有中医药特色的新靶点。

A new study from Karolinska Institutet, published in Science Translational Medicine, shows that people with type 2 diabetes have lower levels of the protein that breaks down and converts creatine ...

Calcineurin fine tunes the balance between proliferation and differentiation of Notch-responsive progenitors in the pancreatic ducts to enable beta cell regeneration in zebrafish.