来自MSN1 个月
Broadly effective vaccine design offers new hope in the fight against hepatitis C
A research team has now achieved promising results. Using epitope-focused immunogens, they were able to induce broadly neutralizing antibodies (bnAbs) in laboratory models for the first time.
Frontiers4 年
Design Concepts of Virus-Like Particle-Based HIV-1 Vaccines
Owing to immunogenic, structural, and functional diversity, virus-like particles (VLPs) could act as efficient vaccine carriers to display HIV-1 immunogens and provide a variety of HIV-1 vaccine ...
Nature4 年
Glycan-masked Engineered Outer Domains of HIV-1 GP120 and Their Use: Collaborative and ...
In conclusion, because of their improved antigenic and immunogenic profiles, glycan-masked eOD-GT8 60mer mutants may serve as improved priming immunogens to elicit VRC01-class bnAbs in humans.
Fred Hutch2 年
IAVI and Moderna launch trial of HIV vaccine antigens delivered through mRNA technology
The induction of bnAbs is widely considered to be a goal of HIV vaccination, and this is the first step in that process. The immunogens being tested in IAVI G002 were developed by scientific teams at ...