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Nature | 基因表达的‘随机性’是健康的屏障还是疾病的推手?
图b则以图示方式概述了常染色体基因的三种可能表达模式:双等位基因表达(BAE),以及单等位基因随机表达中偏向参考等位基因(Ref)或替代等位基因(Alt)的情况。研究者设定了判定单等位表达的阈值,即等位基因不平衡度(AI)≥ 0.80或AI ≤ ...
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