The focus of this month’s blog post is a discussion of malignant peripheral nerve sheath tumors (MPNSTs), which represent one of the few potentially life-threatening complications of neurofibromatosis ...
MPNSTs grow in the soft tissue surrounding nerve cells. They are often associated with neurofibromatosis type 1, a genetic condition caused by a mutation in the tumor-suppressing gene NF1.
In addition to optic gliomas, discussed in last month’s blog, the pediatric NF clinical care guidelines provide a review of the most commonly occurring malignancies in children with NF1; these include ...