Monoamine oxidase inhibitors (MAOIs) have a long and prosperous history as medications for major depressive disorder (MDD). But this type of antidepressant has mostly seen its day. Though MAOIs ...
If currently taking a prescription monoamine oxidase inhibitor (MAOI) (eg, certain drugs taken for depression, psychiatric or emotional conditions, or Parkinson’s disease), or for 2 weeks after ...
In patients receiving serotonergic medications in combination with an MAOI, there have been reports of serious and sometimes fatal reactions, including hyperthermia, rigidity, myoclonus ...
John's Wort) or with drugs that impair serotonin metabolism (eg, MAOIs, linezolid, IV methylene blue). Avoid alcohol. Increased risk of bleeding with concomitant NSAIDs, aspirin, warfarin ...
a MAO-B = monoamine oxidase type B, MAO-A = monoamine oxidase type A. b Expressed as the molar concentration of drug required to inhibit enzyme activity by 50% (nmol/L). c Expressed as the ...