Engineered immune cells called CAR-T cells are used in the treatment of cancer. Researchers from Uppsala University have now ...

通过线粒体转移，癌细胞不仅实现了对T细胞功能的精确抑制，还为其免疫逃逸增加了一道屏障。该研究进一步指出，这种机制与免疫治疗效果不佳密切相关，尤其是在携带大量mtDNA突变的患者中，免疫检查点抑制剂的疗效显著降低。

Lung cancer treatment and outcomes are profoundly influenced by the tumor microenvironment (TME), particularly in resectable ...

Dr. Won Jin Ho presented a talk as part of the Immunology Neighborhood Seminar on “Overcoming the tumor immune ...

Lunit SCOPE® IO now available to SITC members for AI-powered TME profiling, in a collaborative effort to advance cancer ...

We can consider the tumour as a bandit’s base in a village, from which a community of different functional units grows — the millions of cells involved in the tumour microenvironment.

Surrounding these epithelial cells is a microenvironment of supporting cells including stromal cells, such as lung fibroblasts, and tissue resident and transient circulating immune cells.

The tumour microenvironment (TME) provides a supportive niche for cancer to evade therapies and progress towards metastatic disease. In our group we are investigating the components of the TME that ...