Engineered immune cells called CAR-T cells are used in the treatment of cancer. Researchers from Uppsala University have now ...

通过线粒体转移，癌细胞不仅实现了对T细胞功能的精确抑制，还为其免疫逃逸增加了一道屏障。该研究进一步指出，这种机制与免疫治疗效果不佳密切相关，尤其是在携带大量mtDNA突变的患者中，免疫检查点抑制剂的疗效显著降低。

Lung cancer treatment and outcomes are profoundly influenced by the tumor microenvironment (TME), particularly in resectable ...

Dr. Won Jin Ho presented a talk as part of the Immunology Neighborhood Seminar on “Overcoming the tumor immune ...

Lunit SCOPE® IO now available to SITC members for AI-powered TME profiling, in a collaborative effort to advance cancer ...

Surrounding these epithelial cells is a microenvironment of supporting cells including stromal cells, such as lung fibroblasts, and tissue resident and transient circulating immune cells.

An immuno-oncology targeting panel accurately characterized tumor-resident immune cells and located pathologically and clinically relevant tumor microenvironment features. Cancer development and ...

When this protein is expressed in the tumor microenvironment, it is picked up by the immune system's T cells – the warrior cells that are supposed to destroy the cancer cells – suppressing ...