How does our nervous system operate so quickly and efficiently? The answer lies in a membranous structure called myelin. Aa Aa Aa All our activities — eating, walking, talking — are controlled ...

Given compelling links between RXR activation and increased myelin repair, the collaborating scientists employed IRX4204 to investigate the impact of RXR agonism on functional recovery in mice ...

Conditional knock-out mice in which Myrf is knocked out in the OL lineage cells completely fail to develop CNS myelin and exhibit severe neurological symptoms, eventually prematurely dying. Recently, ...

We have recently discovered that mechanical forces generated by the extracellular matrix and other cells are also essential for correct myelination, and we are actively pursuing the molecular ...

Myelin also repairs itself faster in mice models than in humans, which is why the researchers genetically modified the mice ...

Toluidine blue staining. Myelin is stained in blue. The nerve tract is filled with ring-shaped structures, indicating a transverse section of myelinated nerve fibers. (D) Electron microscopy of a ...

The myelin sheath is typically about 100 microns long, with 1 to 2 micron gaps between them.) Recent evidence suggests myelin ...