Vigorous rubbing of the leg or hopping about gradually relaxes ... failed to obtain complete relief from night cramps by the use of quinine sulfate, and the majority of those who obtained relief ...

But the FDA has issued repeated warnings against using quinine to prevent or treat leg cramps because it may cause serious side effects, including severe anemia, bleeding and kidney damage.

Nocturnal leg cramps can occur in all ages ... along with stretching your calf muscles before you go to bed. Failing this, quinine can be very helpful, and can be found in tonic water - try ...

Nocturnal leg cramps- The recommended dose is 200-300 ... The World Health Organization prefers Artemisinin to quinine in treating severe cases of malaria among children, a WHO official said ...

A study reveals vitamin K2 significantly lowers the frequency and intensity of nocturnal leg cramps in individuals over 65, enhancing symptom management.