Overall, the results suggest that dinuclear platinum(II) complexes could offer a more targeted approach to treating prostate cancer, specifically by inhibiting AR-mediated cell growth and survival ...

The dinuclear platinum(II) complexes inhibit prostate cancer cell growth by binding to the androgen receptor (AR) and disrupting AR-mediated gene expression. This mechanism leads to apoptosis and ...

In a recent study, researchers investigated the potential of azolato-bridged dinuclear platinum(II) complexes, particularly 5-H-Y, as promising alternatives. Their findings highlight the complex's ...