OTC Markets Group Welcomes Medicenna Therapeutics Corp. to OTCQX
Group Inc. (OTCQX: OTCM), operator of regulated markets for trading 12,000 U.S. and international securities, today announced ...
Nature5y
Preventing the bubble bursting?
Furthermore, the activity of the metalloprotease MMP2, which is thought to be required for the remodelling involved in aneurysm formation, was significantly reduced in these mice compared with ...
Business Insider12d
Medicenna to Present Clinical and Preclinical Data at the 39th Annual Meeting of the Society for Immunotherapy of Cancer (SITC)
IL-13Rα2 expressing tumors also have abundant matrix metalloprotease in the tumor microenvironment that may efficiently activate MDNA113. IL-13Rα2 expression is associated with poor clinical outcome ...
Pharmaceutical Technology1mon
Neprilysin drugs in development, 2024
GlobalData’s report assesses the drugs in the Neprilysin pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline.
Stockhouse20d
Medicenna Announces Results of Annual Meeting of Shareholders
Medicenna’s early-stage BiSKITsâ„¢ (Bifunctional SuperKine ImmunoTherapies) and the T-MASKâ„¢ (Targeted Metalloprotease Activated SuperKine) programs are designed to enhance the ability of ...
Nature6y
Keeping tabs on fluorescent tags
VisEn Medical has a proprietary fluorescence imaging probe platform that includes the MMPSense probe to detect matrix metalloprotease (MMP) activity in vivo. “This combines FRET-type activation ...
Baylor College of Medicine4y
Intestinal Hormones and the Microbiota
The interplay between the intestinal microbiome and gut hormones is a dynamic and bidirectional relationship. The microbiome influences the production, secretion, and activity of gut hormones, while ...
ALZFORUM12d
Oligodendrocytes Pump Out Aβ42, Worsening Plaques and Synaptotoxicity
Two of the groups reported that cultured human oligodendrocytes make as much or more Aβ than do neurons, and that ...
Financial Post1mon
Medicenna Announces Upcoming Presentations at The Promise of Interleukin-2 Therapy Conference
Medicenna’s early-stage BiSKITs™ (Bifunctional SuperKine ImmunoTherapies) and the T-MASK™ (Targeted Metalloprotease Activated SuperKine) programs are designed to enhance the ability of Superkines to ...
Medscape3d
The Clinical Presentation of Ehlers-Danlos Syndrome
Adv Neonatal Care. 2005;5(6):301-314. Chromosome 7 COL1A2 (collagen, type 2, alpha 2) Same Chromosome 9 COL5A1 (collagen, type 5 alpha 1) Same Chromosome 2 COL5A2 (collagen, type 5, alpha 2) Same ...
Queen Mary University of London6y
Dr Tom Nightingale
Conversely, a failure to appropriately remove VWF from the blood stream due to an inactivity or absence of the shear dependent metalloprotease ADAMSTS13, results in thrombotic thrombocytopenic purpura ...
Medscape1d
The Clinical Presentation of Ehlers-Danlos Syndrome
It is important to identify infants of affected women as high-risk infants. Scrutinize the maternal history and, when possible, determine the specific EDS type of the mother or affected family ...