Sex-hormone derivatives called neurosteroids bind to several receptor types, including GABA A Rs. Maguire and Mody therefore set out to determine whether altered sensitivity of GABA A Rs for ...
Recent data demonstrates that neurosteroids, specifically progesterone (PROG) and some of its metabolites, are neuroprotective in experimental models of traumatic brain injury (TBI). Two recent ...
A long-standing interest concerns the mechanisms by which neurosteroids and oxysterols modulate GABA and glutamate receptors. Clinically, Dr. Zorumski is interested in the treatment of refractory ...
Semin Liver Dis. 2008;28(1):70-80. New technological advances have allowed a better knowledge of the disturbances present in the brain in HE, not only in experimental models, but also in patients ...