"FDA grants IND clearance for Innate Pharma’s solid tumour trial" was originally created and published by Clinical Trials ...

Many types of bacteria produce an enzyme molecule called topoisomerase IV, which disentangles and separates newly replicated ...

Therapy-related acute promyelocytic leukemia (t-APL) is rare and often linked to previous treatment with alkylating agents or topoisomerase II inhibitors. This report describes three cases of t-APL ...

Researchers hope to plan clinical trials of 5-fluorouracil with drugs that would enhance its RNA-damaging effects and kill ...

The breakthrough research was conducted by scientists at the Indian Association for the Cultivation of Science (IACS), ...

Primary target patient population for the CBX-12 Phase 2 study is women with platinum-resistant or refractory ovarian cancer who are naïve to ...

Scientists have identified a promising new target for cancer treatment by activating a DNA repair enzyme called TDP1, ...

Erika P. Hamilton, MD, discusses the patient population with breast cancer enrolled in the TROPION-PanTumor01 trial in ...

Avacta to Unveil Pipeline Expansion and Novel, Next-Generational Targeted Cancer Therapy Programs at 2024 EORTC-NCI-AACR Symposium ...

The bactericidal action of ciprofloxacin results from inhibition of the enzymes topoisomerase II (DNA gyrase) and topoisomerase IV (both Type II topoisomerases), which are required for bacterial ...