2024年9月18日，武汉大学生命科学学院杜世燊研究团队与中国科学技术大学杨新星研究团队在Nature Communications发表了题为“The divisome is a self-enhancing machine in ...

You have full access to this article via your institution. There are several methods for removing MAPs from MTP to produce purified tubulin: using DEAE-Sephadex or phosphocellulose chromatography ...

结肠镜检查是结直肠腺瘤（CRA）诊断的标准方法。但它作为一种侵入性检查，会给患者带来一定的不适感；同时其高昂的操作成本限制了其在大规模筛查中的应用。已有的研究表明使用血浆代谢物进行结直肠癌（CRC）诊断是一种有效可行的方式。然而在腺瘤-癌发展过程中， ...

武汉大学生命科学学院在读博士研究生赵闪及美国NIH国家医学图书馆Kira Makarova博士为该论文的共同第一作者，郑文超和刘雅菲等研究生深入参与了研究，杜世燊研究员与Eugene V.

Scientists reveal how the protein CDK5RAP2 activates a key process that helps cells organize their internal structure. The ...

The work presented will be of interest to cancer biologists and more broadly to those interested in NSCLC translational studies. Non-small cell lung cancer (NSCLC) is the most common subtype of lung ...

In a revealing Genomic Press Interview, Professor Illana Gozes discusses her groundbreaking work on activity-dependent ...

Alentis Therapeutics AG has obtained IND clearance from the FDA for ALE.P02, an anti-Claudin-1 (CLDN1) antibody-drug conjugate (ADC) with a tubulin inhibitor payload.

The primary completion date for the trial is June 2024. The candidate acts by targeting tubulin and cells expressing folate receptor alpha. After binding to cancer cells, the candidate delivers its ...

Androgen deprivation is the mainstay of advanced prostate cancer treatment. Despite initial responses, almost all patients progress to castration-resistant prostate cancer (CRPC). The ...

The advent of large-scale sequencing in both development and disease has identified large numbers of candidate genes that may be linked to important phenotypes. Validating the function of these ...