Angela Wright is missing from Selma, which is 68 miles northeast of Indianapolis, the Silver Alert says. The town is east of ...

Discover the impactful work of Mission 22 in raising awareness of veteran suicide and providing free treatments for veterans ...

A homicide investigation is underway after Indianapolis police say they found a person dead with trauma injuries near an east ...

A remarkable year for downtown Indy. Explore the projects, growth, and milestones that have shaped the city's skyline and ...

Experience the magic of Opera Cabaret with the Indianapolis Opera. Join for a night of opera, musical theater, and jazz at ...

Our lows bottomed out in the mid-40s Wednesday which will have residents thinking: when do we normally get our first frost and first freeze?

Melanoma, which affects the skin, is one of the most common and serious cancers in the U.S. It can be life-threatening.

Swifties big and small are invited to “Par-TAY” with other fans as the Children’s Museum of Indianapolis celebrates the pop ...

This story has been updated to include more information on the search and school lockdowns. Indianapolis police said ...

One of two doctors charged in the investigation of the death of Matthew Perry is expected to plead guilty Wednesday in a ...

What lies beneath the Great Lakes' waves is largely unknown, but there's a new push to learn more about the world's largest freshwater system.

LEAP district investment will total $13 billion, which Lilly touts as the largest single investment in active pharmaceutical ...