*仅供医学专业人士阅读参考众所周知,APOE4是散发阿尔茨海默病(AD)的最强风险基因。大约三年前,首都医科大学宣武医院团队的一项研究显示,亚裔携带APOE4的频率为9%[1]。受影响的人可真不少。去年年底,斯坦福大学团队的一项研究结果表明,APOE ...
当ApoE被传递到转移细胞时,它会中和脂质,当铁死亡开始时脂质会迅速“燃烧”并破坏细胞膜,ApoE会增加细胞的抗氧化能力。综合起来,这些ApoE作用保护黑色素瘤细胞免于溶解,从而降低了体内铁下垂的治疗效果。
A research team led by Prof. Patrizia Agostinis (VIB-KU Leuven) has found that melanoma cell populations protect themselves ...
Researchers from the team of Prof. Patrizia Agostinis (VIB-KU Leuven) have found that melanoma cell populations protect themselves from a form of cell death called ferroptosis by secreting the ...
Revvity's latest solution for specific typing of AD-associated APOE gene is likely to allow assessment of a patient's risk for adverse effects from new anti-amyloid therapy for Alzheimer's.
A study suggests that menopausal hormone therapy (MHT) might have moderate effects on brain health, but this depends on past ...
Revvity, Inc. RVTY announced the launch of the in-vitro diagnostic EURORealTime APOE assay in European countries that accept the CE mark on Oct. 2. The assay will likely enable accurate genotyping ...
A recent study suggests that a drug approved for the treatment of seizures may also help treat Alzheimer's in people who do ...
Late-breaking oral presentation to highlight safety and efficacy of LX1001 across four dose cohorts NEW YORK, Oct. 22, 2024 ...
Recent research is looking at the way in which cardiovascular issue may play into the development of dementia, with one study suggesting that heparin, a common anticoagulant, may help delay ...
Corder, E.H. et al. HIV-infected subjects with the E4 allele for APOE have excess dementia and peripheral neuropathy. Nature Med. 4, 1182–1184 (1998).