In the current treatment era and in the absence of recurrent herpes simplex outbreaks, any value for chronic acyclovir administration, even at the most well-proven dose of 3.2 g/day, is questionable.

OBJECTIVES The frequency and characteristics of the long term sequelae of herpes simplex encephalitis were assessed after treatment with acyclovir. METHODS Patients were included if they were treated ...

HSV and varicella zoster virus (VZV) are common pathogens of skin and mucous membranes and the CNS. Their rapid and accurate diagnosis is essential for their treatment as well as infection control ...