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Mitochondria In Motion Inc. has identified new N-(trans-4-hydroxycyclohexyl)-6-phenylhexanamide derivatives acting as mitofusin activators and reported to be useful for the treatment of Alzheimer’s, ...
Much has been achieved in terms of understanding the complex clinical and genetic heterogeneity of Charcot-Marie-Tooth neuropathy (CMT). Since the identification of mutations ... Nevertheless, despite ...
SAVANNAH, Georgia — There’s no medical treatment for Charcot-Marie-Tooth (CMT) disease ... number of genetically different forms makes diagnosis and genetic therapy difficult, he said ...
OBJECTIVES Charcot-Marie-Tooth disease type I (CMT1) is a hereditary sensorimotor neuropathy causing variable degrees of handicap. The risk for relevant disability in respect to genetic counselling is ...
Two of the best characterized progeroid syndromes are Werner syndrome and Hutchinson–Gilford progeria syndrome (HGPS). The genes targeted for mutation in these diseases (WRN and LMNA ...
With a history of spinal injury and having not undergone a surgical stabilization, a syrinx was suspected. A magnetic resonance imaging (MRI) study of the patient's cervical and thoracic spine was ...
Introduction Damage to peripheral nerves occurs in a variety of health conditions. Preserving nerve integrity, to prevent progressive nerve damage, remains a clinical challenge. Omega-3 ...