The good news: Most of the tested chemicals’ individual cytotoxicity and neurotoxicity levels were relatively low. The bad ...
综上所述,香菇多糖在体外和体内均表现出对Aβ和α-syn纤维聚集的抑制作用,并能够显著缓解其引起的神经毒性和行为缺陷。这些结果表明,香菇多糖可能作为一种潜在的治疗药物用于AD和PD的防治,这一研究为天然多糖类物质在神经退行性疾病中的应用提供了新的思路 ...
Rat LD50 values were taken from the Registry of Toxic Effects of Chemical Substances (RTECS) database [55] and cytotoxicity values were taken from the public National Cancer Institute (NCI ...
免疫系统在肿瘤的发生、发展及治疗过程中扮演着关键角色。传统观点认为,Type-1免疫反应是肿瘤免疫治疗的核心力量,而削弱Type-1免疫应答的Type-2免疫反应通常被视为促进肿瘤进展的因素。以CAR-T细胞疗法和免疫检查抑制剂(Immune ...
For the cytotoxicity model, which was constructed using a large number of records, multitask learning did not affect precision but did reduce computation time. The models developed here were used ...
Antibodies show promise as candidates for therapeutics as well as tools for advancing mechanistic studies of the HER family receptors.
The good news: Most of the tested chemicals' individual cytotoxicity and neurotoxicity levels were relatively low. The bad news: the chemicals acted together to make the entire mixture toxic.
We are honored to welcome Alison to the Artiva Board of Directors. Her decades of executive experience in manufacturing and technical operations across modalities, specifically in allogenic cell ...
Researchers hope to plan clinical trials of 5-fluorouracil with drugs that would enhance its RNA-damaging effects and kill ...
MacroGenics, Inc. (NASDAQ: MGNX), a biopharmaceutical company focused on discovering, developing, manufacturing and ...