Proteolytic enzymes (proteases) have several potential uses, such as aiding digestion, supporting immunity, improving healing, and more. Your body uses these enzymes to break down protein. While your ...

In this study of glucose-mediated mitochondrial repression, the loss of the DUB Ubp3 decreases glycolytic flux by reducing the enzymes at two critical nodes in the pathway - Pfk1 and GAPDH. Unlike ...

By Pooja Toshniwal Paharia Study reveals that moderate fever temperatures (39°C) improve metabolism, proliferation, and ...

Permeabilization of the mitochondria usually leads to caspase activation and apoptosis. In the absence of caspase activation, these same mitochondrial changes can also lead to cell death.

Trypsin enzyme is one of several key enzymes that help digest proteins. People with cystic fibrosis, pancreatitis, or malabsorption may not make enough trypsin enzyme on their own, so they might need ...

By Susha Cheriyedath, M.Sc. Researchers discover a novel protein therapy that recharges exhausted T cells, unleashing their ...

Since the energy supply for mature osteoblasts depends on glycolysis, glycogenic amino acids constitute the raw ... and cause boosted expression of mRNA for the enzymes alkaline phosphatase, ...

The findings are significant for the liver research community and others interested in the gut-liver axis. (A) AOAH cleaves the two piggyback fatty acyl chains from the lipid A moiety, inactivating ...

The primary enzyme in the malate–aspartate shuttle is malate dehydrogenase. Malate dehydrogenase is present in two forms in the shuttle system: mitochondrial malate dehydrogenase and cytosolic malate ...

This article explores the peptide's properties and highlights possible avenues of research where NAD+ might play a crucial role. We focus on areas such as cellular aging, neurodegeneration, circadian ...

Living cells and organisms could not function without enzyme-controlled reactions. The more we understand about how enzymes function and the reactions they control, the better we can use the machinery ...