This article explores the peptide's properties and highlights possible avenues of research where NAD+ might play a crucial role. We focus on areas such as cellular aging, neurodegeneration, circadian ...

Bispecific antibodies (bsAbs) are engineered to target 2 different epitopes simultaneously. About 75% of the 16 clinically ...

By Susha Cheriyedath, M.Sc. Researchers discover a novel protein therapy that recharges exhausted T cells, unleashing their ...

A study led by Brazilian researchers and reported in an article published in the journal Nature Communications proposes that simultaneously targeting the enzyme glutaminase and the protein HuR ...

A study led by Brazilian researchers and reported in an article published in the journal Nature Communications proposes that ...

Proteolytic enzymes (proteases) have several potential uses, such as aiding digestion, supporting immunity, improving healing, and more. Your body uses these enzymes to break down protein. While your ...

In this study of glucose-mediated mitochondrial repression, the loss of the DUB Ubp3 decreases glycolytic flux by reducing the enzymes at two critical nodes in the pathway - Pfk1 and GAPDH. Unlike ...

Trypsin enzyme is one of several key enzymes that help digest proteins. People with cystic fibrosis, pancreatitis, or malabsorption may not make enough trypsin enzyme on their own, so they might need ...

Objective We aim to unveil the consequences of mutant Gnas R201C expression on phenotype, transcriptomic profile and genomic dependencies. Data are available in a public, open access repository. Bulk ...

By Pooja Toshniwal Paharia Study reveals that moderate fever temperatures (39°C) improve metabolism, proliferation, and ...

The metabolic requirements of tumor cells are associated with high levels of glutamine consumption to produce energy. The first step is conversion of glutamine to glutamate catalyzed by glutaminase, ...