Patients with ankylosing spondylitis and IBD exhibit distinct clinical and radiographic features, compared against those without comorbid IBD.

Features linking this group of diseases include association with HLA-B27, peripheral arthritis that is typically asymmetric and lower limb predominant, and possibly include sacroiliitis ...

Fibromyalgia and rheumatoid arthritis can cause similar symptoms like pain, reduced mobility in muscles, and exhaustion. The symptoms may be difficult to distinguish if a person has both conditions.

We think this is a highly genetic-driven disease, with the primary gene involved at this time, we know is HLA-B27. HLA-B27 codes for a protein that is on the surface of inflammation, blood cells.

There is a strong link between the HLA-B27 gene and axial spondyloarthritis. In fact, up to 90% of people with ankylosing spondylitis and 70% of those with nonradiographic axial spondyloarthritis ...

001). HLA-B27 positivity was less likely in women, appearing among 65.8% of women vs. 78.9% of men (P < .001). However, women also reported healthier behaviors than men, with lower proportions of ...

腰痛的成因可以追溯到正常解剖结构的损伤，比如椎体骨折和腰肌劳损，也可能是全身性疾病的炎症引发的结果，如类风湿关节炎和脊柱炎。此外，直接感染、肿瘤的形成、代谢性疾病，甚至某些脏器的问题都可能导致腰部疼痛。例如，孕期由于脊柱负担加重也会造成腰痛。

If iPS cell lines could be derived from donors' somatic cells with an efficiency and safety profile that was comparable to ES cell lines, an opportunity exists to establish more efficient HLA ...