The HBV genome is an extremely compact structure (~3 kb), which encompasses four overlapping ORFs encoding for viral polymerase/reverse transcriptase; the capsid-forming core protein; three ...

Nevertheless, a certain proportion of anti-HBe-positive patients continue to have HBV replication and active liver disease. These patients usually harbor precore/core promoter mutations in the HBV ...

Objective Developing a small animal model that accurately delineates the natural history of hepatitis B virus (HBV) infection and immunopathophysiology is necessary to clarify the mechanisms of ...

Hepatitis and pregnancy is a complicated topic because there are many different types of hepatitis. Hepatitis just means any disease that causes inflammation of the ...

Kahley Schiller's fatigue and nausea symptoms turned out to be acute liver failure end-stage. She shares her story of ...

Gilead Sciences, Inc. (GILD), headquartered in Foster City, California, is a global biopharmaceutical leader known for its ...

Planned industry first clinical trial combining BeiGene's checkpoint inhibitor tislelizumab with Indaptus’ broadly targeted, short duration ...

NHS Highland is about to start a pilot project of opt-out blood borne virus testing in the emergency department in Raigmore ...

Lee Hsien Yang, the youngest son of the late founder of modern Singapore Lee Kuan Yew, said on Tuesday he is now a political refugee, in the latest twist in a high-profile feud in the city-state's ...

GSK has revealed updated results from its phase 2b trial of its antisense drug for hepatitis B virus (HBV) infections, which reveal a sharp decline in the proportion of patients with undetectable ...

GSK’s antisense-based drug for chronic hepatitis B (CHB), bepirovirsen, will get a rapid six-month review from the FDA when it is filed for approval, said the drugmaker this morning. The fast ...