The Spondyloarthritis (Spondyloarthropathy) drugs in development market research report provides ... It can be diagnosed with the help of blood tests identifying HLA-B27 (a gene variant that controls ...

Associated laboratory findings include raised acute phase reactions, HLA-B27 association, and abnormalities on skeletal imaging. Sensitivities, specificities, and likelihood ratios (LRs) of these ...

Moreover, the abundance/prevalence of seven OTUs at baseline may be used as a novel non-invasive index that predicts the response to TNFi with greater accuracy than HLA-B27 status, CRP level and ...

Features linking this group of diseases include association with HLA-B27, peripheral arthritis that is typically asymmetric and lower limb predominant, and possibly include sacroiliitis ...

Spondyloarthritis (SpA), if not diagnosed and treated early, often leads to significant morbidity. Unfortunately, diagnosis and implementation of therapy are frequently delayed, in many cases by ...

Ankylosing spondylitis (AS), Spondyloarthropathies’ (SpA) prototype, is a common, highly heritable inflammatory arthritis characterized by enthesitis of the spine and sacroiliac joints. AS aetiology ...

Six (17%) patients had a family history of spondyloarthropathy, 14 (40%) had previous uveitis, 21 (60%) had peripheral joint disease, one (3%) had inflammatory bowel disease, nine (26%) had psoriasis, ...

30 Vitamin D receptor gene may contribute to BMD differences in patients with AS, and some polymorphisms are also linked to inflammation.32–34 The HLA B27 transgenic rat, a validated model of ...

Psoriatic arthritis (PsA) is a type of inflammatory arthritis that affects the joints and entheses (the connective tissue between bone and tendons or ligaments). Common symptoms of PsA are joint pain, ...

Ankylosing spondylitis (AS), known as the prototype of the spondyloarthropathy group, is a chronic inflammatory rheumatic ... BMI, human leukocyte antigen-B27 (HLA-B27) positivity, duration of ...