Among the non-infectious causes, drug-induced hypersensitivity reactions are rare but serious. Isoniazid, a cornerstone in tuberculosis treatment, is known for its hepatotoxicity but has rarely been ...
This work focuses on the application of biophysical techniques to assess the interaction of isoniazid (INH) with three-dimensional cell membrane mimetic models. Liposomes made of ...
A team of Indian researchers have developed a unique way to deliver Tuberculosis (TB) drugs directly to the brain bypassing the challenging blood-brain barrier (BBB) that limits the effectiveness of ...
Genomic analysis studies reveal that isoniazid resistance overwhelmingly develops earlier than resistance to other antituberculosis drugs. When rifampicin resistance is detected, pre-existing ...