Interleukin 6 (IL6) is a pleiotropic cytokine with a wide range of biological activities ... Successful treatment of the model animals for immune-inflammatory diseases with anti-IL6 receptor (IL6R) ...

Although RA is associated with significant morbidity, the increasing number of effective drugs and modes of action has improved the disease outcome. Currently, several US Food and Drug Administration ...

Methods Peripheral blood mononuclear cells (PBMC) from 61 patients with SLE and 52 healthy donors and in vitro IL-2 stimulated PBMC were characterised by multicolour flow cytometry. Five patients with ...

Merck & Co/MSD has agreed to buy Pandion for $1.85 billion, bolting on a pipeline of drugs for autoimmune and other immunological disorders headed by interleukin-2 (IL-2) based therapy PT-101.

Pharmaceutical Institute, Pharmacology and Toxicology, University of Bonn, Gerhard-Domagk-Str. 3, 53121 Bonn, Germany ...

The three-signal paradigm tries to capture how the innate immune system instructs adaptive immune responses in three well-defined actions: (1) presentation of antigenic peptides in the context of MHC ...

India struggled to 164/5 at stumps on Day 2 of the Boxing Day Test in Melbourne, trailing Australia by 310 runs. After a solid 102-run partnership between Yashasvi Jaiswal (82) and Virat Kohli (36 ...

The list includes several groundbreaking therapies that are expected to change the treatment landscape for several diseases and conditions.

We hypothesised that patients with community acquired pneumonia (CAP) associated with systemic inflammatory response syndrome (SIRS) would have greater interleukin 6 (IL-6) production due to ...