The odds ratio for exposure to L-dopa in the IPD patients with PN was 12.4 (95% confidence interval, 1.4–109.1). There were no differences between the groups in the use of other PD drugs ...

NLX-101 (F15599) is under development for the treatment of Rett syndrome and depression. The drug candidate is administered by oral route. The drug candidate is a new chemical entity (NCE). The drug ...

Mavoglurant is under development for the treatment of cocaine use disorder, alcohol use disorder and for language learning in young children with fragile X syndrome (FXS). The drug candidate is ...

L-dopa remains the most powerful antiparkinsonian agent, but a minority of treated patients develop disabling motor response complications. Alternatives to L-dopa for initial treatment of ...

U of A researchers have uncovered new findings about involuntary muscle movements that come with long-term administration of Parkinson's drug levodopa.

During the course of the disease, virtually all patients developed asymmetric or unilateral akinetic rigid parkinsonism and a gait disorder. No patient had a dramatic response to levodopa therapy.

Standard Parkinson's treatment does not always prevent tremors, which affect up to 90 per cent of those with the disease, ...

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Investigations. Measurement of levels of serum phosphate, parathyroid hormone, ionized calcium and insulin; measurement of peak growth hormone by the arginine–levodopa stimulation test ...