A new mini review was published in Oncotarget's Volume 15 on September 30, 2024, entitled, “Linking FOXM1 and PD-L1 to CDK4/6 ...
The focus of this month’s blog post is a discussion of malignant peripheral nerve sheath tumors (MPNSTs), which represent one of the few potentially life-threatening complications of neurofibromatosis ...
The Financial Express on MSN7mon
Neurofibromatosis (NF1) Symptoms and Diagnosis: What to Look for and How to Get TestedRadiation therapy or chemotherapy for malignant peripheral nerve sheath tumours (MPNSTs) or optic pathway gliomas. Regular ...
News Medical on MSN15d
The role of FOXM1 and PD-L1 in malignant peripheral nerve sheath tumor resistanceCurrently, MPNSTs lack effective therapies. Recently, the authors demonstrated the remarkable efficacy of dual CDK4/6-MEK ...
In addition to optic gliomas, discussed in last month’s blog, the pediatric NF clinical care guidelines provide a review of the most commonly occurring malignancies in children with NF1; these include ...
We suggest that future therapeutic strategies targeting the oncogenic network of CDK4/6, MEK, PD-L1, and FOXM1 represent ...
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