Each study arm was included as intervention and segregated into guideline-recommended regimens (cyclophosphamide (CYC), mycophenolic acid analogues (MPAAs), calcineurin inhibitors and belimumab) or ...

The new guideline emphasizes the importance of prompt kidney biopsy and LN treatment. Triple therapy is proposed as the most desirable therapy, preferring mycophenolic acid analog (MPAA) regimens to ...

In a new study published in Lupus Science & Medicine, researchers reviewed randomized clinical trials (RCTs) to assess ...

Autoantibodies are one of the distinguishing features of AIH. The discovery of autoantibodies directed against different cellular targets, including endoplasmatic reticulum membrane proteins ...

Aim: Little information is available regarding the influence of CYP3A5 genetic polymorphisms on tacrolimus dose requirement in pediatric liver transplantation. Patients & methods: We performed a ...

Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease which, if untreated, often leads to cirrhosis, liver failure and death. Major advances were made in its management based on ...

1 Department of Dermatology, University of Texas Southwestern Medical School, Dallas, TX, USA 2 Baylor University Medical Center, Dallas, TX, USA Quality of life studies in patients with cutaneous ...

All patients received mycophenolate mofetil (MMF) (target dose 2–2.5 g/day or equivalent dose of mycophenolic acid). Protocol-mandated corticosteroid treatment included methylprednisolone (a total of ...

Also in his surgical history was a right hemithyroidectomy for a cold thyroid nodule and parathyroidectomy for a parathyroid adenoma. His immunosuppressive medications were mycophenolic acid, ...

Most patients received induction therapy, consisting in basiliximab (49.3%) or thymoglobulin (47.4%). All patients received maintenance immunosuppression with tacrolimus, mycophenolic acid and ...