A study that evaluated the natural history of bisphosphonate-related osteonecrosis of the jaw (ONJ)—an emergent problem for certain patients with cancer—found that reinitiation of ...
The drugs Fosomax, Actonel, Boniva and Reclast, which are called bisphosphonate drugs have been associated with a new, newly recognized condition, called osteonecrosis of the jaw. Now let me say ...
Cellus Inc. has disclosed compounds acting as disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS4; aggrecanase-1) and 5 (ADAMTS5; aggrecanase-2) inhibitors reported to be useful ...
Besides pain, other symptoms include swelling, fever, mobility difficulties, and chills. Insufficient blood supply to the hip causes the bones to die, a process known as osteonecrosis. Osteonecrosis ...
and bone loss in the jaw (osteonecrosis). Some evidence suggests long-term use may actually increase the risk of a certain type of fracture. The modest benefits of the drugs combined with their ...
Other common diagnoses include rheumatoid arthritis, other types of inflammatory arthritis, post-traumatic arthritis, and osteonecrosis of the femoral head. Patients that are candidates for THA ...