Anti-histamines combined with a decongestant are usually marked with a "D." Claritin-D, Allegra-D, and Zyrtec-D all contain a decongestant called pseudoephedrine, the same active ingredient that ...
Getty Images Antihistamine pills like Zyrtec, Claritin or Allegra are more effective than topical creams, as they calm the body’s overall immune response.