Results Patient 1: Anifrolumab effectively treated refractory chronic cutaneous lupus erythematosus with lupus panniculitis and calcinosis cutis. Patient 2: Anifrolumab demonstrated rapid improvement ...

Anti-MJ antibodies, which recognise the nuclear protein NXP-2 in PML (promyelocytic leukemia) nuclear bodies, are a new specificity reported in 23–25% of juvenile DM, usually associated with severe ...

Face and Skin Calcium deposits on the face and skin can be caused by certain autoimmune disorders, kidney disease, acne, and calcium medications. These types of calcium deposits are called calcinosis ...

Nanobacteria have been at the center of a major scientific controversy in recent years owing to claims that they represent not only the smallest living microorganisms on earth but also new ...

Brain MRI: A/D - T1 hyperintense signal in the basal ganglia and dentate nuclei; B/E - T2 low to isointense signal in the basal ganglia and dentate nuclei; C/F - SWI hyposignal in the basal ganglia, ...

Moreover, ATK vessels tend to be more elastic and less muscular than BTK arteries and frequently have less uniform medial calcinosis; these properties alter the ability for endoluminal drug delivery ...

Calcinosis occurred in 6% (78/1314) of cases overall but was more common in those with JDM (44% (23/52) of JDM vs 4% (55/1262), OR 17.4, 95% CI 9.45 to 32.04, p<0.001) and CTD-overlap myositis (10% ...

Atherosclerosis is an inflammatory process that results in the accumulation of fatty or necrotic residues in the vessel wall. This leads to fibroplasia and calcinosis, causing thickening and hardening ...

Non-specific skin manifestations are also seen in patients with SLE, including non-scarring alopecia, urticarial vasculitis, livedo reticularis and calcinosis.1 These conditions are not frequently ...

Scleroderma is a rare and complex autoimmune disease that leads to the tightening and hardening of the skin and connective tissues. This condition, also known as systemic sclerosis, results from the ...