Objective To assess the efficacy of anifrolumab, a type-1 interferon receptor subunit-1 monoclonal antibody, in treating refractory cutaneous lupus erythematosus (CLE) and lupus non-specific ...
Nucleic acids derived from microorganisms or dying host cells are recognized by Toll-like receptor 7 (TLR7), TLR8 and TLR9 in endo-lysosomal compartments. In the cytoplasm, there are several ...