The authors examine the role of Numb, a Notch inhibitor, in intestinal stem cell self-renewal in Drosophila during homeostasis and regeneration. This is an important study providing evidence of a Numb ...

Here the authors use a single-cell genomics approach to show that ileal pouches from ulcerative colitis patients feature a unique type of enterocytes which express colonocyte-specific and ...

Shigella infection can cause severe discomfort in humans, emphasizing the need for mechanisms to understand it. With new technologies and animal models, you can see how far life science researchers ...

Hereditary hemochromatosis is an inherited iron overload disorder caused by inappropriately low hepcidin secretion leading to increased duodenal absorption of dietary iron, most commonly in C282Y ...