This study addresses the effects of estrogen on the kisspeptin1 subset of neurons in the arcuate nucleus of the hypothalamus of female mice after ovaries were surgically removed. The authors repeat ...

This important study combined multiple approaches to gain insight into why rising estradiol levels, by influencing hypothalamic neurons, ultimately lead to ovulation. The experimental data were robust ...

Figure 1: Uterine histology in aged female wild–type and Bax –/– mice. Figure 2: Ovarian histology in aged female wild–type and Bax –/– mice. Figure 3: Ovarian histology of aged Bax ...