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Nat Cell Biol | HSF1调控NK细胞抗肿瘤免疫
引言多种细胞损伤都会导致热休克因子HSF1的激活,HSF1是一种胁迫响应的转录因子,调节蛋白毒性应激反应,维持细胞蛋白稳态,此外,HSF1还以细胞类型特异性和环境特异性的方式调节许多其他基因程序,并具有促肿瘤效应。但是HSF1在肿瘤微环境免疫细胞类群 ...
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