Beijing Key Laboratory of Active Substances Discovery and Druggability Evaluation, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, ...

Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, Saint Louis, Missouri 63104, United States Institute for Drug and Biotherapeutic Innovation, Saint Louis ...

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Differentiated thyroid cancers (DTC) and anaplastic thyroid cancers (ATC) often develop primary and acquired resistance to standard treatments. This highlights the need for new therapeutic strategies ...

Cancer cells must have access to pyrimidine supplies to produce more cancer cells and to produce uridine nucleotides, a primary fuel source for cancer cells as they rapidly reproduce, grow, and die.

Shuttle Pharmaceuticals Holdings, Inc. (NASDAQ:SHPH – Get Free Report)’s share price fell 0.7% on Wednesday . The company traded as low as $0.61 and last traded at $0.61. 40,294 shares were traded ...

Additionally, the contribution of pyrimidine nucleotides (such as UTP and UDP) and sugar-nucleotides (i.e., UDP-glucose and UDP-galactose) have been more recently discovered. Purinergic signaling ...

Laboratory experiments with cancer cells reveal two ways in which tumors evade drugs designed to starve and kill them, a new ...

Azacitidine is under clinical development by Bristol-Myers Squibb and currently in Phase II for Pancreatic Ductal Adenocarcinoma.