Researchers have discovered how egg cells prepare for life by studying the Balbiani body, a structure that organizes key ...

While women’s genetic makeup makes them more prone to autoimmune diseases, are there other factors contributing to the ...

Researchers have uncovered how egg cells prepare for the creation of life. Their work reveals the secrets of the Balbiani ...

Cas9-based ribonucleoproteins engineered via directed evolution and encapsulated in optimized lipid nanoparticles improve genome-editing efficacies in the livers and lungs of mice.

▎药明康德内容团队编辑  本周，顶尖学术期刊《细胞》发布了2024年度的最佳论文（Best of 2024）特辑，精选了过去一年《细胞》杂志发表的论文中，“最有趣”“最有影响力”并且“引起广泛关注”的生物学研究。杂志主编John W.

The CONNECT2-EDO51 phase 2 trial looks at PGN-EDO51, an investigational therapy for Duchenne muscular dystrophy (DMD), and is still ongoing in the United Kingdom. The most-read gene therapy ...

For this, ACSS2 and ACLY were deleted from naïve gp33-specific transgenic TCR P14+ CD8+ 5 T cells using single-guide (sg) RNAs with Cas9 ribonucleoproteins (RNPs) (CRISPR-Cas9/RNP) via ...

References [1]Hassfeld W, Steiner G, Graninger W, et al. Autoantibody to the nuclear antigen RA33: a marker for early rheumatoid arthritis.Br J Rheumatol 1993;32(3):199-203. [2]Caporali R, Bugatti S, ...

This important study addresses how 3' splice site choice is modulated by the conserved spliceosome-associated protein Fyv6. The authors provide compelling evidence that Fyv6 functions to enable ...

Zhejiang Key Laboratory of Smart Biomaterials and Center for Bionanoengineering, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou Zhejiang 310058, China ...