Background Treatment to suppress or lessen effects of puberty are outlined in clinical guidelines for adolescents experiencing gender dysphoria/incongruence. Robust evidence concerning risks and ...

Obsessive-compulsive disorder (OCD) in childhood and adolescence is an impairing condition, associated with a specific set of distressing symptoms incorporating repetitive, intrusive thoughts ...

Introduction An overview is given on the use of microdosing/microtracing studies for the safer and faster development of drugs in children. In a microdosing study a ...

2 Charles Salt Research Centre, Robert Jones and Agnes Hunt Orthopaedic & District Hospital NHS Trust, Oswestry, Shropshire SY10 7AG, UK 3 Department of Clinical Chemistry, University of Oulu, Oulu, ...

AIMS To evaluate the effects of discontinuing growth hormone (GH) treatment on energy expenditure and body composition, which might help predict those most likely to benefit from early reintroduction ...

School of Women’s and Children’s Health, University of New South Wales, Sydney, Australia Dr K Lui, Department of Newborn Care, Royal Hospital for Women, Barker Street, Randwick, New South Wales, ...

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Objective To determine the incidence, causes and neurodevelopmental impact of severe microcephaly (head circumference <–3SD) up to age 2 years. Design Binational active paediatric surveillance study ...

Background Children's medicines are not always readily available as an age appropriate product and manipulation of adult products is often required. Recently the commercial manufacturing process for ...