Introduction NICE recommends faecal calprotectin (FCP) testing as an option to support clinicians with the differential diagnosis of inflammatory bowel disease (IBD) or irritable bowel syndrome (IBS) ...

Correspondence to Dr Johann von Felden, Department of Internal Medicine, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany; j.von-felden{at}uke.de; Dr Augusto Villanueva, Liver Cancer Program, ...

Objective To compare efficacy of pharmacotherapies for chronic idiopathic constipation (CIC) based on comparisons to placebo using Bayesian network meta-analysis. Data sources We conducted searches ...

1 Center for Esophageal Diseases and Swallowing, University of North Carolina Schools of Medicine and Public Health, Chapel Hill, NC, USA 2 Veterans’ Administration Center for Practice Management and ...

Background Sphingosine Kinase (SphK) is a key rate-limiting enzyme that catalyzes sphingosine phosphorylation to generate sphingosine-1-phosphate (S1P) and plays a critical role in protecting mice ...

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Correspondence to Brian B Scott, Department of Medicine, Lincoln County Hospital, Lincoln LN2 5QY, UK; drbbscott{at}aol.com Iron deficiency anaemia (IDA) occurs in 2–5% of adult men and postmenopausal ...

Background Breast cancer is an ongoing issue that is plaguing many young women especially within the regions of Asia. Many factors have been studied thoroughly and have been ruled out over the years.

1 Institute of Biomedical and Clinical Sciences, St James’s University Hospital, University of Leeds, Leeds, UK 4 Institute of Cancer and Pathology, St James’s University Hospital, University of Leeds ...

Correspondence to Professor Changqing Yang, Division of Gastroenterology and Hepatology, Tongji Hospital, Tongji University School of Medicine, Shanghai, 389 XinCun Road, Shanghai 200065, China; ...

Correspondence to Dr Samuel Pannick, Gastroenterology, Imperial College Healthcare NHS Trust, London W6 8RF, UK; sam.pannick{at}nhs.net A 55-year-old woman was referred for investigation of an ...

Objective To evaluate the potential for diagnosing colorectal cancer (CRC) from faecal metagenomes. Design We performed metagenome-wide association studies on faecal samples from 74 patients with CRC ...