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腾讯网
1 天
Cell | TEX264驱动的选择性自噬促进DNA修复和细胞存活
01 英国牛津大学拉德克利夫医院的研究团队在Cell杂志上发表了一篇论文,发现TEX264介导的核吞噬作用在维持基因组稳定性和细胞存活中发挥关键作用。
生物谷
14 天
Cell:新研究发现TEX264促进受损DNA修复和细胞存活的机制
具体而言,研究者发现在脊椎动物中,溶酶体处理拓扑异构酶1裂解复合物(lysosomes process topoisomerase 1 cleavage complex, TOP1cc)促进DNA损伤。自噬对 TOP1cc ...
生物谷
16 天
2024年9月Cell期刊精华
一项新的研究表明在婴儿出生后的第一年里,母乳不仅能提供营养,还能调节婴儿的微生物组合(即微生物组),从而降低孩子患哮喘的风险。相关研究结果发表在2024年9月19日的 Cell 期刊上,论文标题为 “Microbial colonization ...
Too Old to Operate
1 天
Therapy-Related Acute Promyelocytic Leukemia: Case Series and Current Insights.
Therapy-related acute promyelocytic leukemia (t-APL) is rare and often linked to previous treatment with alkylating agents or topoisomerase II inhibitors. This report describes three cases of t-APL ...
GEN
7 天
Old Chemo Drug Is New Again Because It Can Attack Different Cancers Differently
Researchers hope to plan clinical trials of 5-fluorouracil with drugs that would enhance its RNA-damaging effects and kill ...
devdiscourse
4 天
New Study Uncovers Dual Target for Overcoming Drug Resistance in Cancer Cells: CDK1 and TDP1
The breakthrough research was conducted by scientists at the Indian Association for the Cultivation of Science (IACS), ...
来自MSN
10 天
X-ray scattering technique pinpoints new targets for antibiotic drug development
Many types of bacteria produce an enzyme molecule called topoisomerase IV, which disentangles and separates newly replicated ...
India Education Diary
5 天
New cancer therapy target could help patients overcome resistant to current treatments
Scientists have identified a promising new target for cancer treatment by activating a DNA repair enzyme called TDP1, ...
Targeted Oncology
15 小时
FDA Clears IND of Novel ADC in AML Treatment
BL-M11D1, a CD33-binding antibody-drug conjugate, is being evaluated for the treatment of patients with acute myeloid ...
4 天
Avacta to Unveil Pipeline Expansion and Novel, Next-Generational Targeted Cancer Therapy ...
Avacta to Unveil Pipeline Expansion and Novel, Next-Generational Targeted Cancer Therapy Programs at 2024 EORTC-NCI-AACR Symposium ...
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